Focus On: Wild African Mango
Recently showcased on the Dr. Oz show, the West African herb also known as Irvingia gabonensis (latin for African Mango) has medical and natural health researchers clamoring over the possible positive health implications it would extend to various factions within the United States.
Used as a daily food source for centuries in Africa, a number of published studies confirm two distinct side effects of this herb if taken—resistance to diabetes and obesity. This exciting herb has multi-dimensional regulation of a number of different chemicals, metabolic pathways (PPARy and glycerol-3, phosphate), genes that influence the production of hormones, and enzymes that control metabolism. It also inhibits C-reactive protein elevation and regulation of adiponectin and leptin. Furthermore, the African mango lowers total cholesterol and LDL (harmful cholesterol), and stabilizes blood glucose. With its 14-percent fiber content, Wild African Mango improves elimination and also suppresses your appetite.
There are a number of beneficial substances and nutrients found in Wild African Mango. An analysis of the seeds and pulp revealed an eight-percent protein content and the presence of 18 amino acids. This herb also has an 11-percent carbohydrate content, while packed with abundant sources of vitamins, calcium, magnesium, potassium, sodium, iron, and phosphorus.
While its fat content is high at 66 percent, about 95 percent of those fatty acids are in the forms of myristic, lauric, and palmitic acids. These are the same fatty acids found in coconut oil. The significance is that, over the last decade, these fats prove to be beneficial (fat burning, cholesterol lowering, and metabolized more efficiently for fuel) to the point that they are now considered as viable options to trans-fatty acids formed and used during hydrogenation processes in the manufacturing of oils and margarines. As you know, trans-fatty acids are commonly referred to as natural born killers, one of heart disease's best friends.
The Scientific Jargon
C-reactive protein is a protein produced by the liver. When the protein is elevated, it signals alarming rates of inflammation throughout the body, which are linked to a number of negative long-term health conditions such as cancer, elevated cholesterol levels, heart disease, rheumatoid arthritis, weight gain, and obesity.
Adiponectin is a hormone found in fat cells that revs up the body’s metabolic rate, which converts food to energy at a faster rate and discourages fat storage. Adiponectin also modulates and balances the actions of the hormones neuropeptide Y and ghrelin. Neuropeptide Y increases appetite while ghrelin keeps appetite cravings on an even keel and discourages overeating.
Leptin regulates excessive food cravings, body heat, and improves metabolism so that calories burn faster.
Glycerol-3phosphate dehydrogenase is an enzyme that enables glucose to be stored as triglycerides in fatty tissue.
Peroxisome proliferators activated receptors (PPAR) is one of those proteins, yes proteins, found in fat cells that play the lead roll in initiating and reactivating adipogenesis, which is the formation of fat cells.
Astounding Study Results
Over the last couple of decades, astounding study results regarding Wild African Mango have caught everyone’s attention. For example, in a recent 10-week double-blind, placebo-controlled study, subjects who took Wild African Mango lost 28.1 pounds of weight compared to 1.5 pounds from the placebo group, with an accompanying reduction of body fat by 6.3 percent compared to 1.9 percent in the placebo group. Collective data has also revealed that individuals’ supplemental use of this herb resulted in cholesterol levels dropping by up to 27 percent compared to 4.8 percent in the placebo groups. Also in a double-blind, randomized study at the Department of Biochemistry at the University of Yaounde in Cameroon, 40 subjects with an average age of 42 saw an 11.7-pound weight reduction compared to 2.9 pounds in the placebo group.
In addition to weight loss, researchers report that study subjects experience corresponding drops in cholesterol by 39.2 percent, triglycerides by 44.9 percent, elevation of HDL (good cholesterol) by 46.8 percent, and an overall reduction in blood glucose levels of 32.3 percent, as compared to little to no change within the placebo groups.
150 mg twice daily before meals up to 1000 mg three times a day before meals. I would suggest starting at the low-end range and adjust your dose based on your specific outcomes.