Health Tips: 5 or More Cups of Coffee a Day Reduce Success of In Vitro Fertilization

Women who drink five or more cups of coffee a day severely reduce their chance of success from in vitro fertilization treatment. The study showed that the consumption of five or more cups of coffee a day reduced the clinical pregnancy rate by 50 percent and the live birth rate by 40 percent.

“Although we were not surprised that coffee consumption appears to affect pregnancy rates in IVF, we were surprised at the magnitude of the effect,” said Ulrik Schiøler Kesmodel, PhD, from the Fertility Clinic of Aarhus University Hospital in Denmark.

In their conclusion, the authors compared the adverse effect of five cups of coffee “to the detrimental effect of smoking.” Several recent studies and reviews have indicated that tobacco smoking has an adverse effect in IVF on the number of oocytes retrieved, and rates of fertilisation, implantation, pregnancy, and live birth.

“The fact that we found no harmful effects of coffee at lower levels of intake is well in line with previous studies on time-to-pregnancy and miscarriage, which also suggest that, if coffee does have a clinically relevant effect, it is likely to be upwards from a level of four-to-six cups a day.”