Health News: New Findings in Insulin Production

Scientists have found three new and relatively rare genetic variants that influence insulin production. They offer new clues about the genetic factors behind diabetes, according to research published online in Nature Genetics.

The study revealed that variants of three genes—TBC1D30, KANK1, and PAM—are associated with abnormal insulin production or processing, even in people without diabetes. The genes may predispose such individuals to developing the disease.

This is the first time genetic insights have been reported using exome array genotyping, a new tool that is less costly than genetic sequencing. This analysis allows scientists to quickly screen DNA samples for known variants in specific genes.