Health News: Fish Peptide Inhibits Cancer Metastasis

A peptide (protein) identified recently by a group of researchers at the University of Maryland School of Medicine and derived from Pacific cod may inhibit the spread of prostate, and possibly other cancers. Hafiz Ahmed, PhD, said, “The use of natural dietary products with antitumor activity is an important and emerging field of research. Understanding how these products work could allow us to develop foods that also act as cancer therapeutics and agents for immunotherapy.”

Polar fish express glycoproteins rich in an antigen called TFD, which protects them from freezing. The research team developed a special form of TFD called TFD100, purified from Pacific cod. The researchers observed that TFD100 prevents cancer cells from attaching to the vessel walls, suppresses T-cell death, and boosts the immune response.